The role of the HIF-1α/ALYREF/PKM2 axis in glycolysis and tumorigenesis of bladder cancer.

Jing-Zi WangWei ZhuJie HanXiao YangRui ZhouHong-Cheng LuHao YuWen-Bo YuanPeng-Chao LiJun TaoQiang LuJi-Fu WeiHaiwei Yang

Published in: Cancer communications (London, England) (2021)

The m5C modification in PKM2 mRNA in the HIF-1α/ALYREF/PKM2 axis may promote the glucose metabolism of bladder cancer, providing a new promising therapeutic target for bladder cancer.

Keyphrases

endothelial cells