A subpopulation of spikes predicts successful epilepsy surgery outcome.
John ThomasPhilippe KahaneChifaou AbdallahTamir AvigdorWillemiek J E M ZweiphenningStephan ChabardesKassem JaberVéronique LatreilleLorella MinottiJeff HallFrançois DubeauJean GotmanBirgit FrauscherPublished in: Annals of neurology (2022)
Resection of brain regions with high spike-gamma rates in wakefulness is associated with a high probability of achieving seizure freedom. This rate could be applied to determine the minimal number of spiking channels requiring resection. In addition to quantitative analysis, this feature is easily accessible to visual analysis, which could aid clinicians during presurgical evaluation. This article is protected by copyright. All rights reserved.