Inflammation and micronutrient biomarkers predict clinical HIV treatment failure and incident active TB in HIV-infected adults: a case-control study.
Rupak ShivakotiNikhil GupteSrikanth TripathySelvamuthu PoongulaliCecilia KanyamaSima BerendesSandra W CardosoBreno R SantosAlberto La RosaNoluthando MwelaseSandy PillayWadzanai SamanekaCynthia RivierePatcharaphan SugandhavesaRobert C BollingerAshwin BalagopalRichard D SembaParul ChristianThomas B CampbellAmita Guptanull nullPublished in: BMC medicine (2018)
Factors identified through EFA were associated with adverse outcomes in HIV-infected individuals. Strategies focused on reducing adverse HIV outcomes through therapeutic interventions that target the underlying factor (e.g., inflammation) rather than focusing on an individual observed biomarker might be more effective and warrant further investigation.