Efficient inference of homologs in large eukaryotic pan-proteomes.
Siavash Sheikhizadeh AnariDick de RidderM Eric SchranzSandra SmitPublished in: BMC bioinformatics (2018)
We clearly observed the trade-off between recall and precision in our homology inference. Favoring recall or precision strongly depends on the application. The clustering behavior of our program can be optimized for particular applications by altering a few key parameters. The program is available for public use at https://github.com/sheikhizadeh/pantools as an extension to our pan-genomic analysis tool, PanTools.