Daylight photodynamic therapy of actinic keratosis without curettage is as effective as with curettage: a randomized clinical trial.

Daylight PDT without curettage but with 1 h of MAL incubation before daylight exposure was shown to be as effective in treatment of thin AKs on the face and scalp as standard daylight PDT with curettage. This modification of daylight PDT eases the task for the clinic and makes it more convenient for the patients as well, creating the possibility of performing daylight PDT as an entirely home-based treatment for AKs of the face and scalp without training the patients to perform pretreatment.