Gonadal tumor development in 46,XX disorders of gonadal development.
Mariana CostanzoMaría Sol TouzonRoxana MarinoGabriela GuercioPablo RamirezMaría Celeste MattoneNatalia Pérez GarridoMaría Marcela BailezElisa VaianiMarta CiaccioMaría Laura Galluzzo MuttiAlicia BelgoroskyEsperanza BerenszteinPublished in: European journal of endocrinology (2022)
46,XX disorders of gonadal development are historically considered at a low risk for germ cell cancer, and the need for assessment of gonadal histology has been questioned. The finding of early germ cell malignancies in our cohort brings awareness and needs further research.