Therapeutic drug monitoring of amikacin in preterm and term neonates with late-onset sepsis. Can saliva samples replace plasma samples?

Amadou Samb Fleur SinkelerYuma A BijleveldAnton van KaamTimo R de HaanRon Mathôt

Published in: British journal of clinical pharmacology (2023)

TDM of amikacin using saliva samples results in target attainment comparable to plasma samples and may be beneficial for (premature) neonates with LOS.

Keyphrases

late onset
low birth weight
early onset
preterm infants
intensive care unit
acute kidney injury
gestational age
septic shock