The Golden Hour: Sustainability and Clinical Outcomes of Adequate Time to Antibiotic Administration in Children with Cancer and Febrile Neutropenia in Northwestern Mexico.
Miriam L GonzalezPaula AristizabalAdriana Loera-ReynaDara TorresMario Ornelas-SánchezLaura Nuño-VázquezMarco AguileraAlicia SánchezMitzy RomanoRebeca Rivera-GómezGeorge RelyeaPaola FriedrichMiguela A CanizaPublished in: JCO global oncology (2021)
Our results demonstrate that locally adapted multimodal interventions can reduce TTA in resource-constrained settings. Mentoring and dissemination were novel components of the multimodal strategy to improve FN-associated clinical outcomes. Improving local infrastructure, ongoing monitoring systems, and leadership engagement have been key factors to achieving sustainability during the 5-year period.