Composite Biomarkers, Behavioral Symptoms, and Comorbidities in Axial Low Back Pain: A Systematic Review.

Anitha Saravanan Jinbing BaiPrempreet BajajElizabeth SternerMahalakshmi RajagopalSameera SandersAnne LuckoseMichael KushnickAngela R Starkweather

Published in: Biological research for nursing (2023)

Proinflammatory cytokines in aLBP can serve as composite biomarkers for pain, associated symptoms, and comorbidities and may serve as a target for future interventions. There is need for well-designed studies assessing associations among chronic inflammation, behavioral symptoms, and comorbidities.

Keyphrases

oxidative stress
sleep quality
chronic pain
physical activity
pain management
spinal cord injury
current status
depressive symptoms
case control
drug induced