Clinical and computed tomography characteristics of non-small cell lung cancer with ALK gene rearrangement: Comparison with EGFR mutation and ALK/EGFR-negative lung cancer.
Mio MoriHideyuki HayashiMinoru FukudaSumihisa HondaTakeshi KitazakiKazuto ShigematsuNaohiro MatsuyamaMayumi OtsuboTakeshi NagayasuMikiko HashisakoKazuhiro TabataMasataka UetaniKazuto AshizawaPublished in: Thoracic cancer (2019)
NSCLC with ALK gene rearrangement was more likely to develop in younger women with a light or never smoking history. The characteristic CT findings of NSCLC with ALK gene rearrangement were a large solid mass, less air bronchogram, a central location, and lymphadenopathy.
Keyphrases
- advanced non small cell lung cancer
- small cell lung cancer
- epidermal growth factor receptor
- computed tomography
- copy number
- genome wide
- tyrosine kinase
- genome wide identification
- magnetic resonance imaging
- positron emission tomography
- dual energy
- contrast enhanced
- transcription factor
- gene expression
- genome wide analysis
- pet ct