Combination of Haploidentical Hematopoietic Stem Cell Transplantation with Umbilical Cord-Derived Mesenchymal Stem Cells in Patients with Severe Aplastic Anemia: A Retrospective Controlled Study
Xian-Fu ShengHui LiLi-Li HongHai-Feng ZhuangPublished in: Turkish journal of haematology : official journal of Turkish Society of Haematology (2022)
In multivariate analysis, graft failure was the only adverse predictor for OS. Meanwhile, graft failure, grades III-IV acute GVHD, and moderate-severe chronic GVHD could predict worse GFFS. Our results indicated that haplo-HSCT combined with UC-MSCs infusion was an effective and safe option for SAA patients.
Keyphrases
- umbilical cord
- mesenchymal stem cells
- end stage renal disease
- allogeneic hematopoietic stem cell transplantation
- chronic kidney disease
- drug induced
- newly diagnosed
- ejection fraction
- early onset
- bone marrow
- acute myeloid leukemia
- liver failure
- stem cell transplantation
- peritoneal dialysis
- low dose
- emergency department
- high intensity
- data analysis
- acute respiratory distress syndrome
- cord blood
- high dose
- hepatitis b virus
- iron deficiency