Immune predictors of hepatitis B surface antigen seroconversion in patients with hepatitis B reactivation.
Mojahidul IslamJayesh Kumar SevakManoj Kumar SharmaAnkur JindalAshish Kumar VyasMeenu BajpaiGayatri RamakrishnaShiv Kumar SarinNirupama TrehanpatiPublished in: Alimentary pharmacology & therapeutics (2022)
Non-seroconverters have increased inhibitory markers on CD4/CD8 T cells. There is a critical play of CD8, Tfh and B cells and subsets in seroclearance, along with checkpoint molecules as a potential therapy for non-seroconverters in HBV infection.