Adding the Optic Nerve in Multiple Sclerosis Diagnostic Criteria.
Ángela Vidal-JordanaAlex RoviraWillem Guillermo Calderon MirandaGeorgina ArrambideJoaquín CastillóDulce MonchoKimia RahnamaSara ColloroneAhmed E OthmanOlga CiccarelliAthina PapadopoulouNuria Cerdá-FuertesJohanna M LiebSerena RuggieriCarla TortorellaClaudio GasperiniAlvino BiseccoRocco CapuanoAntonio GalloAndrea De BarrosAnnalaura SalernoCristina AugerJaume Sastre-GarrigaMar TintoreXavier MontalbanPublished in: Neurology (2023)
In patients with CIS, the presence of an optic nerve lesion defined by MRI, OCT, or VEP is frequently detected, especially when presenting with optic neuritis. Our study supports the addition of the optic nerve as a fifth topography to fulfill DIS criteria.