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Facilitated osteogenesis of magnesium implant by coating of strontium incorporated calcium phosphate.

Jung-Eun ParkYong-Seok JangJae-Min SeoMin-Ho Lee
Published in: Biointerphases (2023)
This study investigated the corrosion resistance and biocompatibility of magnesium coated with strontium-doped calcium phosphate (Sr-CaP) for dental and orthopedic applications. Sr-CaP was coated on biodegradable magnesium using a chemical dipping method. Magnesium coated with Sr-CaP exhibited better corrosion resistance than pure magnesium. Sr-CaP-coated magnesium showed excellent cell proliferation and differentiation. Additionally, new bone formation was confirmed in vivo. Therefore, Sr-CaP-coated magnesium with reduced degradation and improved biocompatibility can be used for orthopedic and dental implant applications.
Keyphrases
  • cell proliferation
  • drug delivery
  • quantum dots
  • oral health
  • signaling pathway
  • high resolution
  • metal organic framework
  • atomic force microscopy