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A phase 2, randomized trial evaluating the combination of dalantercept plus axitinib in patients with advanced clear cell renal cell carcinoma.

Martin H VossRupal S BhattNicholas J VogelzangMayer FishmanRobert S AlterBrian I RiniJ Thaddeus BeckMonika JoshiRalph HaukeMichael B AtkinsEarle BurgessTheodore F LoganDavid ShafferRahul ParikhNauman MoazzamXiaosha ZhangChad GlasserMatthew L ShermanElizabeth R Plimack
Published in: Cancer (2019)
Although well tolerated, the addition of dalantercept to axitinib did not appear to improve treatment-related outcomes in previously treated patients with advanced RCC.
Keyphrases
  • metastatic renal cell carcinoma
  • renal cell carcinoma
  • type diabetes
  • adipose tissue
  • combination therapy
  • skeletal muscle
  • replacement therapy