Whole exome germline sequencing in early-onset prostate cancer patients: Genomic findings and clinical outcomes.

Nava Siegelmann-DanieliVictoria NeimanAvital Bareket-SamishRacheli BergerAsaf PeretzHillel AlapiErez TsurTal PatalonDaniella BellerGalit RimlerGabriel ChodickMordechai Shohat

Published in: The Prostate (2023)

In this cohort of 134 early-onset prostate cancer patients, we identified germline LP/P variants in an oncogenetic panel in 6% of participants, with no unique clinical outcome.

Keyphrases

early onset
copy number
prostate cancer
late onset
benign prostatic hyperplasia
dna repair
single cell
genome wide
dna methylation