Evaluating Hepatobiliary Transport with 18F-Labeled Bile Acids: The Effect of Radiolabel Position and Bile Acid Structure on Radiosynthesis and In Vitro and In Vivo Performance.
Stef De LombaerdeKen KersemansSara NeytJeroen VerhoevenChristian VanhoveFilip De VosPublished in: Contrast media & molecular imaging (2018)
A set of 18F labeled bile acids was synthesized that are substrates of the bile acid transporters in vitro and in vivo and can serve as PET-biomarkers for hepatobiliary transport of bile acids.