Reproductive failure in an Austrian piglet-producing farm due to porcine circovirus genotype 2d.
Johannes ReifRené RenzhammerRené BrunthalerChristiane Weissenbacher-LangAngelika AuerHeinrich KreutzmannRobert FuxAndrea LadinigChristine UnterwegerPublished in: Acta veterinaria Hungarica (2022)
Infections of pigs with porcine circovirus type 2 (PCV2) can lead to various clinical conditions including reproductive disorders (PCV2-RD). In general, a transplacental infection of fetuses leads to mummification and stillbirth. So far, PCV2-RD has mainly been described in specific-pathogen-free (SPF) herds or farms with a high proportion of gilts. From December 2018 to February 2019, a high abundance of mummified fetuses (15.5%) was observed in two farrowing groups in an Austrian piglet-producing farm. PCV2 DNA was detected using qPCR in organs of all six investigated fetuses (2.07 × 108-1.09 × 1012 PCV2) genome equivalents/g tissue and via in situ hybridisation in organs from five fetuses, while histologic lesions were not observed in a single fetal heart. All isolates were sequenced and identified as PCV2d. After the implementation of a regular vaccination of all sows against PCV2, the abundance of mummified fetuses dropped to 3.5% in May 2019. In contrast to previous reports about PCV2-RD, this farm was neither an SPF herd nor a start-up herd with a high proportion of gilts. The implementation of regular PCV2 vaccination helped to reduce the abundance of mummified fetuses substantially.
Keyphrases
- gestational age
- primary care
- healthcare
- quality improvement
- gene expression
- computed tomography
- magnetic resonance imaging
- circulating tumor
- dna methylation
- high resolution
- atrial fibrillation
- genome wide
- cell free
- candida albicans
- preterm birth
- microbial community
- contrast enhanced
- high speed
- atomic force microscopy
- drug induced