Suppression of AGR2 in a TGF-β-induced Smad regulatory pathway mediates epithelial-mesenchymal transition.
Lucia SommerovaEva OndrouskovaBorivoj VojtesekRoman HrstkaPublished in: BMC cancer (2017)
Taken together our results highlight a crucial role for AGR2 in maintaining the epithelial phenotype by preventing the activation of key factors involved in the process of EMT.