Effects of Aripiprazole on Olanzapine Population Pharmacokinetics and Initial Dosage Optimization in Schizophrenia Patients.

Cun ZhangLei JiangKe HuLiang ChenYi-Jia ZhangHao-Zhe ShiSu-Mei HeXiao ChenDong-Dong Wang

Published in: Neuropsychiatric disease and treatment (2024)

Aripiprazole significantly affected olanzapine clearance, and when schizophrenia patients use aripiprazole, the olanzapine dosages need adjust. Meanwhile, we firstly recommended the optimal initial dosages of olanzapine in schizophrenia patients.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
bipolar disorder
peritoneal dialysis
prognostic factors
chemotherapy induced