Characterization of an oligometastatic state in patients with metastatic pancreatic adenocarcinoma undergoing systemic chemotherapy.
Saryleine de Ortiz de ChoudensAlexis VisotckyAnjishnu BanerjeeMohammed AldakkakSusan TsaiDouglas B EvansKathleen K ChristiansCallisia N ClarkeBen GeorgeAditya ShreenivasMandana KamgarSakti ChakrabartiKulwinder S DuaAbdul Haq KhanSrivats MadhavanBeth A EricksonWilliam A HallPublished in: Cancer medicine (2023)
In this exploratory analysis normalization of CA-19-9 or volumetric metastatic disease burden less than 0.2 cc demonstrated a remarkable OS, similar to that of patients with non-metastatic disease. These metrics are useful for counseling patients and identifying cohorts that may be optimal for trials exploring metastatic and/or local tumor-directed interventions.
Keyphrases
- squamous cell carcinoma
- small cell lung cancer
- end stage renal disease
- newly diagnosed
- ejection fraction
- physical activity
- peritoneal dialysis
- locally advanced
- radiation therapy
- risk factors
- patient reported outcomes
- hepatitis c virus
- smoking cessation
- patient reported
- hiv testing
- human immunodeficiency virus
- drug induced