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Development and utility of a clinical research informatics application for participant recruitment and workflow management for a return of results pilot trial in familial hypercholesterolemia in the Million Veteran Program.

Charles A BrunetteThomas YiMorgan E DanowskiMark CardellinoAlicia HarrisonThemistocles L AssimesJoshua W KnowlesKurt D ChristensenAmy C SturmYan V SunQin HuiSaiju PyarajanYunling ShiStacey B WhitbourneJ Michael GazianoSumitra MuralidharJason L Vassy
Published in: JAMIA open (2024)
The development of usable, customizable, and secure informatics tools will become increasingly important as large genomic repositories begin to return research results at scale. Our work provides a proof-of-concept for developing and using such tools to aid in managing the return of results process within a national biobank.
Keyphrases
  • quality improvement
  • electronic health record
  • big data
  • copy number
  • dna methylation