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A Preliminary Investigation on a Commercial Ovine Pasteurellosis Vaccine Using Clinical and Pathological Endpoints.

Mersha AsfawMenur SenbitMohammed YesufMelkie Dagnaw FentaGirma BirhanAnmaw Shite AbatSaddam Mohammed Ibrahim
Published in: Infection and drug resistance (2022)
Collectively, the results suggested that the vaccine posed no safety concern and presumably lacks protective efficacy against local isolates. However, the study did not analyze antibody titer and their functionality using serum bactericidal assays. Further confirmatory studies could provide more evidence on the vaccine efficacy. Safety should further be assessed in a field setting involving a large number of animals to enable detection of rare vaccine adverse events.
Keyphrases
  • sensitive detection
  • genetic diversity