Markers of atopic dermatitis, allergic rhinitis and bronchial asthma in pediatric patients: correlation with filaggrin, eosinophil major basic protein and immunoglobulin E.
Zafar RasheedKhaled ZedanGhada Bin SaifRagaa H SalamaTarek SalemAhmed A AhmedAlaa Abd El-MoniemMaha ElkholyAhmad A Al RobaeeAbdullateef A AlzolibaniPublished in: Clinical and molecular allergy : CMA (2018)
These findings strongly support a role of filaggrin protein, eosinophil MBP and IgE in the onset of allergic reactions in pediatric patients with AD, AR and BA. The data suggest that filaggrin, eosinophil MBP or IgE might be useful in evaluating the progression of AD, AR or BA and in elucidating the mechanisms involved in the pathogenesis of these pediatric disorders.