The NOS1AP gene rs10494366 common genetic variant does not modify the risk of sudden cardiac death in users of digoxin.

Negin SoroushAlbert-Jan AarnoudseMaryam KavousiJan A KorsM Arfan IkramBruno H StrickerFariba Ahmadizar

Published in: British journal of clinical pharmacology (2024)

Current use of digoxin is associated with a significantly increased risk of SCD. The NOS1AP gene rs10494366 variant did not modify the digoxin-associated risk of SCD in a population of European ancestry.

Keyphrases

genome wide
copy number
transcription factor
nitric oxide synthase
genome wide identification
dna methylation
nitric oxide
gene expression
genome wide analysis