Spontaneous-Breathing Trials with Pressure-Support Ventilation or a T-Piece.
Arnaud W ThilleArnaud GacouinRémi CoudroyStephan EhrmannJean-Pierre QuenotMai-Anh NayChristophe GuittonDamien ContouGuylaine LabroJean ReignierGael PradelGaëtan BeduneauLaurence DangersClement SaccheriGwénaël PratGuillaume LacaveNicholas SedillotNicolas TerziBéatrice La CombeJean-Paul MiraAntoine RomenMarie-Ange AzaisAnahita RouzéJérôme DevaquetAgathe DelboveMartin DresJeremy BourenneAlexandre LautretteJoe de KeizerStéphanie RagotJean-Pierre Fratnull nullPublished in: The New England journal of medicine (2022)
Among patients who had a high risk of extubation failure, spontaneous-breathing trials performed with PSV did not result in significantly more ventilator-free days at day 28 than spontaneous-breathing trials performed with a T-piece. (Supported by the French Ministry of Health; TIP-EX ClinicalTrials.gov number, NCT04227639.).