Randomized Phase III Trial Evaluating Radiation Following Surgical Excision for Good-Risk Ductal Carcinoma In Situ: Long-Term Report From NRG Oncology/RTOG 9804.
Beryl McCormickKathryn A WinterWendy A WoodwardHenry M KuererNour SneigeEileen RakovitchBarbara L SmithIsabelle GermainAlan C HartfordMark Allen O'RourkeEleanor M WalkerEric A StromJudith O HopkinsLori J PierceAnthony T PuKenneth N M SumidaDanny VespriniJennifer MoughanJulia R WhitePublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2021)
RT significantly reduced all and invasive IBR for good-risk DCIS with durable results at 15 years. These results are not an absolute indication for RT but rather should inform shared patient-physician treatment decisions about ipsilateral breast risk reduction in the long term following lumpectomy.