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MicroRNA-708 Suppresses Cell Proliferation and Enhances Chemosensitivity of Cervical Cancer Cells to cDDP by Negatively Targeting Timeless.

Xinwei ZouChenjie ZhuLin ZhangYi ZhangFengqing FuYouguo ChenJinhua Zhou
Published in: OncoTargets and therapy (2020)
We conclude that miR-708 suppresses cell proliferation, facilitates cisplatin efficacy, and impairs DNA repair pathway in cervical cancer cells. These results demonstrate that miR-708 might be a candidate therapeutic target for future cervical cancer therapy.
Keyphrases
  • cell proliferation
  • dna repair
  • cancer therapy
  • cell cycle
  • dna damage
  • signaling pathway
  • pi k akt
  • drug delivery
  • long non coding rna
  • dna damage response
  • long noncoding rna