Proteomics-based identification of TMED9 is linked to vascular invasion and poor prognoses in patients with hepatocellular carcinoma.

Yi-Chieh YangMing-Hsien ChienTsung-Ching LaiMin-Che TungYi-Hua JanWei-Ming ChangShih-Ming JungMing-Huang ChenChun-Nan YehMichael Hsiao

Published in: Journal of biomedical science (2021)

Ours is the first work to identify an oncogenic role of TMED9 in HCC cells and may provide insights into the application of TMED9 as a novel predictor of clinical outcomes and a potential therapeutic target in patients with HCC.

Keyphrases

induced apoptosis
cell cycle arrest
mass spectrometry
transcription factor
endoplasmic reticulum stress
human health
oxidative stress
risk assessment
bioinformatics analysis
pi k akt
cell proliferation