Characteristics of Induced-Sputum Inflammatory Phenotypes in Adults with Asthma: Predictors of Bronchial Eosinophilia.
Astrid Crespo-LessmannElena CurtoEder Freddy Mateus MedinaEsther PalonesAlicia Belda SolerSoraya Sánchez MazaLorena Soto-RetesVicente Plaza MoralPublished in: Journal of asthma and allergy (2023)
In consultations for severe asthma, the most frequent phenotype was eosinophilic. Peripheral blood eosinophilia is a reliable marker for discriminating between different bronchial inflammatory phenotypes, is useful in enabling doctors to select a suitable biologic treatment and so prevent asthma exacerbation, and is a better predictor of bronchial eosinophilia than FeNO and IgE values.
Keyphrases
- chronic obstructive pulmonary disease
- peripheral blood
- lung function
- oxidative stress
- cystic fibrosis
- allergic rhinitis
- high glucose
- mycobacterium tuberculosis
- diabetic rats
- primary care
- endothelial cells
- air pollution
- acute respiratory distress syndrome
- respiratory failure
- extracorporeal membrane oxygenation
- smoking cessation