Harnessing endogenous peptide compounds as potential therapeutics for severe influenza.
Alison C WestChristopher M HarpurMélanie A Le PageMaggie LamChristopher HodgesLauren K ElyAndrew J GearingMichelle D TatePublished in: The Journal of infectious diseases (2023)
These findings provide preclinical evidence that therapeutic LAT9997 treatment limits viral burden and characteristic features of severe influenza, including hyperinflammation and lung damage.