Modelling Anti-Ov16 IgG4 Antibody Prevalence as an Indicator for Evaluation and Decision Making in Onchocerciasis Elimination Programmes.

Yvonne L LontLuc E CoffengSake J de VlasAllison GoldenTala de Los SantosGonzalo J DomingoWilma A Stolk

Published in: PLoS neglected tropical diseases (2017)

Better understanding of the dynamics of Ov16 antibody responses is required for accurate interpretation of seroprevalence data and more precise estimation of endpoint for MDA. Our study demonstrates that this endpoint will be dependent on baseline endemicity levels, which should be taken into account in guidelines for defining when to stop MDA.

Keyphrases

breast cancer cells
risk factors
electronic health record
high resolution
cell cycle arrest
clinical practice
machine learning
artificial intelligence
mass spectrometry
deep learning