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Bifunctional naringenin-laden gelatin methacryloyl scaffolds with osteogenic and anti-inflammatory properties.

Lais M CardosoAna Beatriz G de CarvalhoCaroline AnselmiAbdel H MahmoudRenan Dal-FabbroFernanda G BassoMarco C Bottino
Published in: Dental materials : official publication of the Academy of Dental Materials (2024)
GelMA+NA5 % scaffold was cytocompatible, stimulated aBMSCs proliferation and differentiation, and downregulated inflammatory mediators' synthesis, suggesting its therapeutic effect as a multi-target bifunctional scaffold with osteogenic and anti-inflammatory properties for bone tissue engineering.
Keyphrases
  • tissue engineering
  • anti inflammatory
  • mesenchymal stem cells
  • bone marrow
  • highly efficient
  • bone mineral density
  • signaling pathway
  • oxidative stress
  • metal organic framework
  • bone loss
  • body composition