Efficacy of immune-checkpoint inhibitors in metastatic gastric or gastroesophageal junction adenocarcinoma by patient subgroups: A systematic review and meta-analysis.

Yulia KundelMichal SternschussAssaf MooreGali PerlBaruch BrennerHadar Goldvaser

Published in: Cancer medicine (2020)

Compared to standard treatment, ICIs in metastatic gastric/GEJ adenocarcinoma did not improve OS. None of the evaluated subgroups has shown increased magnitude of effect to ICIs, aside of the small group with MSI-H tumors.

Keyphrases

squamous cell carcinoma
small cell lung cancer
locally advanced
case report
combination therapy
radiation therapy