The hepatotoxicity of γ-radiation synthesized 5-fluorouracil nanogel versus 5-fluorouracil in rats model.

Wael Em BarakatFatma S M Moawed Esraa S A AhmedOmayma Ar Abo-Zaid

Published in: International journal of immunopathology and pharmacology (2024)

Consequently, 5-Fu nanogel exhibited lower liver toxicity compared to 5-FU, likely due to the alleviation of hepatic inflammation and the regulation of the cellular redox pathway.

Keyphrases

oxidative stress
oxide nanoparticles
drug induced
radiation induced
radiation therapy