S100P contributes to promoter demethylation and transcriptional activation of SLC2A5 to promote metastasis in colorectal cancer.

Mingdao LinYuan FangZhenkang LiYongsheng LiXiaochuang FengYizhi ZhanYuwen XieYuechen LiuZehao LiuGuoxin Li Zhiyong Shen Haijun Deng

Published in: British journal of cancer (2021)

Our results reveal a novel mechanism that S100P mediates the promoter demethylation and transcription activation of SLC2A5, thereby promoting the metastasis of CRC.

Keyphrases

transcription factor
gene expression
dna methylation
genome wide