In-Vivo Degradation of DNA-Based Therapeutic BC 007 in Humans.

Hanna DavideitSusanne BeckerJohannes MüllerNiels-Peter BeckerPeter GöttelAyşe AbayAngela SinnMatthias GrossmannMarkus MallekAnnekathrin HaberlandHardy Weisshoff

Published in: European journal of drug metabolism and pharmacokinetics (2019)

Fast and full degradation of BC 007, shown by nucleic bases degradation products, is one of the first reports about the fate of a ssDNA product in humans.

Keyphrases

single molecule
emergency department
adverse drug