Intraoperative MRI-derived volumetric ablation margins and initial correlation with local outcome after MRI-guided cryoablation of renal tumors.
Nienke S de JagerTim J van OostenbruggeTorben PätzSjoerd F M JenniskensJurgen J FüttererJohan F LangenhuijsenChristiaan G OverduinPublished in: Cancer imaging : the official publication of the International Cancer Imaging Society (2023)
Determination of volumetric ablation margins from intraoperative MRI was feasible and may be useful in predicting local outcome after MRI-guided renal cryoablation. In our preliminary data, an intraoperative MRI-derived minimal margin extending at least 1 mm beyond the MRI-visible tumor led to local control and this was more difficult to achieve in tumors > 3 cm. Ultimately, online margin analysis may be a valuable tool to intraoperatively assess therapy success, but larger prospective studies are needed to establish a reliable threshold for clinical use.