Serpin family proteins as potential biomarkers and therapeutic drugs in stroke: A systematic review and meta-analysis on clinical/preclinical studies.

Bing YanLu LuoLi LiuZhenyu WangRuiying ChenYi WuXiao Xiao

Published in: CNS neuroscience & therapeutics (2023)

Our study confirmed the important roles serpin family proteins played in the onset, progression, and treatment of stroke. Among serpins, AT and TAT may be used as blood biomarkers in the early diagnosis of stroke. C1-INH and FUT175 could be potential medications for IS.

Keyphrases

atrial fibrillation
cerebral ischemia
bone marrow
climate change
drug induced
replacement therapy
brain injury
subarachnoid hemorrhage
cell therapy
risk assessment
mesenchymal stem cells