Methylated miRNAs may serve as potential biomarkers and therapeutic targets for hidradenitis suppurativa.
Uppala RadhakrishnaU RatnamalaD D JhalaN VadsariaM PatelL V UppalaS VishweswaraiahA VedangiN SaiyedG DamianiG B E JemecPublished in: Journal of the European Academy of Dermatology and Venereology : JEADV (2022)
Epigenetically altered microRNA genes are implicated in wound healing, inflammation, keratinocyte proliferation and wound modulation. This is the first study to analyse methylation profiles of miRNA genes in the HS population, highlighting the unique role that miRNAs might play in diagnosing and treating HS.