Gene expression study and pathway analysis of histological subtypes of intestinal metaplasia that progress to gastric cancer.

Osmel CompanioniJosé Miguel Sanz-AnquelaMaría Luisa PardoEulàlia PuigdecanetLara NonellNadia GarcíaVerónica Parra BlancoConsuelo LópezVictoria AndreuMiriam CuatrecasasMaddi GarmendiaJavier P GisbertCarlos A GonzalezNúria Sala

Published in: PloS one (2017)

There are greater differences in gene expression and molecular processes involved in the progression from normal healthy mucosa to IM than from IM to gastric cancer. While antigen processing is common in both IM-subtypes progressing to GC, more oncogenic processes are observed in the progression of IIM.

Keyphrases

gene expression
dna methylation
transcription factor
single molecule
high resolution
solid phase extraction