Effectiveness and safety of methotrexate in the treatment of mycosis fungoides: Real-world data from a multicentre study.

Vasiliki A Nikolaou Evdoxia Panou Antonios Tsimpidakis Ioannis-Alexios Koumprentziotis Aikaterini PatsatsiMarina SiakantarisSabine-Elke Kruger-KrasagakisLeonidas MarinosElisavet GeorgiouKyriaki LampadakiAliki VelissariAthina-Ioanna DaponteAikaterini DoxastakiStella Kaliampou Aristeidis G VaiopoulosIliana KonstandinouMarios KoumourtzisEleftheria LakiotakiVassiliki PappaAthanasios TsamaldoupisAlexander StratigosEvangelina Papadavid

Published in: Journal of the European Academy of Dermatology and Venereology : JEADV (2024)

Our findings support MTX as a viable treatment option for MF, particularly when used in the first-line setting, offering a favourable benefit/risk profile. Response rates are stage-dependent, with erythrodermic patients achieving superior and durable responses.

Keyphrases

end stage renal disease
chronic kidney disease
newly diagnosed
prognostic factors
big data
combination therapy
machine learning
low dose
patient reported outcomes
deep learning
smoking cessation