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Enriched Single-Nucleus RNA-Sequencing Reveals Unique Attributes of Distal Convoluted Tubule Cells.

Xiao-Tong SuJeremiah V ReyesAnne E LackeyHasan DemirciSebastian BachmannYujiro MaeokaRyan J CorneliusJames A McCormickChao-Ling YangHyun Jun JungPaul A WellingJonathan W NelsonDavid H Ellison
Published in: Journal of the American Society of Nephrology : JASN (2024)
Transcriptomic analysis of an enriched rare cell population using a genetically targeted approach clarifies the function and classification of distal cells. The DCT segment is short, can be separated into two subsegments that serve distinct functions, and is speculated to derive from different origins during development.
Keyphrases
  • induced apoptosis
  • single cell
  • cell cycle arrest
  • minimally invasive
  • machine learning
  • endoplasmic reticulum stress
  • rna seq
  • deep learning
  • stem cells
  • signaling pathway
  • oxidative stress
  • cell therapy
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