The Lnc-RNA APPAT Suppresses Human Aortic Smooth Muscle Cell Proliferation and Migration by Interacting With MiR-647 and FGF5 in Atherosclerosis.
Fan-Ming MengLuyang HanQin LiangShanshan LuYanqing HuangJunwen LiuPublished in: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists (2022)
could suppress the migration and proliferation of ox-LDL-treated HASMCs via interacting with miR-647 and FGF5. We revealed a nontypical competing endogenous RNA mechanism of long noncoding RNA in the progression of atherosclerosis.
Keyphrases
- long noncoding rna
- smooth muscle
- single cell
- signaling pathway
- cardiovascular disease
- endothelial cells
- protein kinase
- cell proliferation
- aortic valve
- long non coding rna
- cell therapy
- pulmonary artery
- nucleic acid
- left ventricular
- type diabetes
- heart failure
- stem cells
- mesenchymal stem cells
- pulmonary hypertension
- pulmonary arterial hypertension