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Should insulin resistance (HOMA-IR), insulin secretion (HOMA-β), and visceral fat area be considered for improving the performance of diabetes risk prediction models.

Huanhuan HuTohru NakagawaToru HondaShuichiro YamamotoTetsuya Mizoue
Published in: BMJ open diabetes research & care (2024)
This cohort study, primarily composed of male workers, suggests that a model with BMI, FPG, and HbA1c effectively identifies those at high diabetes risk. However, adding HOMA-IR, HOMA-β, or replacing BMI with VFA does not significantly improve the model. Further studies are needed to confirm our findings.
Keyphrases
  • insulin resistance
  • type diabetes
  • glycemic control
  • adipose tissue
  • cardiovascular disease
  • body mass index
  • metabolic syndrome
  • high fat diet
  • skeletal muscle
  • polycystic ovary syndrome
  • weight loss