Implementing an integrated community based health systems strengthening approach to improve HIV survival in Northern Togo.
Kevin Peter FioriHayley M BelliMolly E LauriaLisa R HirschhornJennifer SchechterEmily HansmanNandita RajshekharVenance KatinSesso GbeleouMeskerem Grunitsky-BekeleVincent Palokinam PitchePublished in: AIDS care (2019)
To disseminate lessons learned from the implementation experience of a public-private sector partnership, we describe a comprehensive HIV/AIDS program including 5-year survival outcomes for individuals who initiated antiretroviral therapy (ART) treatment in Togo from 2010 to 2015. A retrospective case study analysis was conducted from a cohort of patients receiving ART at an HIV/AIDS care clinic in Kara Region, Togo. Kaplan-Meier curves with Log rank tests were used to compare estimated survival curves by demographic and clinical characteristics. Associations were described between survival probability and age, gender, World Health Organization (WHO) disease stage, and timing of ART initiation. Cox proportional hazard model was used to determine predictors of mortality. After approximately five-years since ART initiation (1780 days), there were 114 deaths, with a survival probability of 75.3% (95% CI: 70.3-80.6%). Participants with advanced WHO disease stage were more likely at risk of death relative to patients categorized as WHO Stage 1, with Stage 4 approximately 9 times more likely (aHR 9.22, 95% CI 4.29-19.84). Our study suggests that delivering comprehensive HIV care through a private-public partnership may serve as a model to expand and improve HIV/AIDS care as well as high quality primary care.
Keyphrases
- hiv aids
- antiretroviral therapy
- hiv infected
- healthcare
- human immunodeficiency virus
- hiv positive
- primary care
- hiv infected patients
- quality improvement
- mental health
- end stage renal disease
- free survival
- health insurance
- chronic kidney disease
- newly diagnosed
- ejection fraction
- emergency department
- peritoneal dialysis
- prognostic factors
- affordable care act
- smoking cessation