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Evaluation of insertion/deletion (I/D) polymorphisms of ACE gene and circulating levels of angiotensin II in congenital anomalies of the kidney and urinary tract.

Pedro Antunes PousaTamires Sara Campos MendonçaLarissa Marques FonsecaMaria Christina L OliveiraAndré Rolim BelisárioAna Cristina Dos Santos Lopes
Published in: Molecular biology reports (2022)
Although CAKUT is a complex disease and the ACE gene may exert a role in kidney embryogenesis, CAKUT was not associated with any ACE I/D polymorphisms nor with differences in plasma levels of Ang II in this Brazilian pediatric population.
Keyphrases
  • angiotensin ii
  • angiotensin converting enzyme
  • urinary tract
  • vascular smooth muscle cells
  • genome wide identification
  • copy number
  • genome wide
  • transcription factor
  • gene expression