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The relationship of peritubular capillary density with glomerular volume and kidney function in living kidney donors.

Jessica van der WeijdenPatrick A de HoogtM M E LeufkensAnke A KeijbeckHarry Van GoorMarius C van den HeuvelJ P M CleutjensCyril MoersMaarten Gj SnoeijsGerjan J NavisMarco van LondenIlja Maria NolteStefan P BergerMartin H de BorstCarine J Peutz-Kootstra
Published in: Journal of nephrology (2023)
In summary, peritubular capillary density was not related to unstimulated kidney function before or after kidney donation, in contrast to glomerular volume. However, number of peritubular capillaries/tubule correlated with the increase in glomerular filtration rate after dopamine stimulation in healthy kidneys, and with glomerular volume. These findings suggest that peritubular capillary density and glomerular volume differentially affect kidney function in healthy living kidney donors.
Keyphrases
  • diabetic nephropathy
  • high glucose
  • magnetic resonance
  • metabolic syndrome
  • computed tomography