Angiotensin-II-Type-1a Receptor (AT1aR) and Renal K+ Wasting during Overnight Low-Na+ Intake.

Xin-Peng DuanJun-Ya ZhengYu XiaoCheng-Biao ZhangDao-Hong Lin Wen-Hui Wang

Published in: Journal of the American Society of Nephrology : JASN (2024)

Acute Ang-II or overnight-LS stimulated Kir4.1/Kir5.1 in late-DCT and that AT1aR was responsible for acute Ang-II or overnight-low-salt-induced stimulation of Kir4.1/Kir5.1 and NCC. AT1aR of the DCT plays a role in maintaining adequate baseline renal-EK and plasma K+ concentrations during overnight-LS.

Keyphrases

angiotensin ii
liver failure
angiotensin converting enzyme
drug induced
vascular smooth muscle cells
respiratory failure
weight gain
physical activity
intensive care unit
endothelial cells
body mass index
weight loss