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DLBCL of bilateral submandibular glands and MALToma of thyroid-A rare coexistence.

Pritika KushwahaMeeta SinghShramna MandalShruti DhingraShyama Jain
Published in: Cytopathology : official journal of the British Society for Clinical Cytology (2021)
Involvement of the bilateral submandibular glands and thyroid by the same lymphoma simultaneously has been reported in the literature. However, two different types of lymphomas presenting simultaneously at different sites have never been reported. This case report highlights this rare occurrence. A 65-year-old female, a known case of Hashimoto's thyroiditis with raised anti-TPO antibodies, presented with thyroid swelling for 1 year and bilateral submandibular swelling for 3 years. FNAC and flow cytometry showed features of mucosa-associated lymphoid tissue lymphoma in the thyroid gland, whereas the bilateral submandibular glands showed features of diffuse large B cell lymphoma. Histopathology and immunohistochemistry from the submandibular swelling led to similar diagnoses as the flow cytometry.
Keyphrases
  • diffuse large b cell lymphoma
  • flow cytometry
  • case report
  • epstein barr virus
  • systematic review
  • risk assessment